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About the Job:

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible.

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping or teams accelerate progress. Join our Translational Disease Modeling (TDM) group as a Principle Scientist and you'll support our R&D portfolio with mechanistic modeling or Quantitative Systems Pharmacology approaches.

This position Is based in Cambridge, MA.

Main Responsibilities:

• Function as part of a team to develop and implement multiscale computational models of complex diseases based on detailed biological mechanistic knowledge.

• Identify and leverage relevant preclinical and clinical data to incorporate into models.

• Survey literature to gain understanding of critical physiological processes to be represented, and identify suitable mechanistic elements, data, parameters and assumptions to be included.

• Analyze internal preclinical and clinical data to inform modeling activities.

• Analyze simulation results and identify suitable strategies to resolve issues pertaining to model performance and accuracy.

• Maintain extensive documentation of model development process, and data analysis.

• Maintain quantitative systems pharmacology expertise through comprehensive education including attendance and participation in conferences, scientific workshops etc.

• Communicate modeling predictions to key stakeholders.

About You:

• PhD with an excellent track record of productivity in the areas of systems pharmacology/biology, computational biology, biomedical engineering or related field, as manifested by publications and scientific presentations in prestigious conferences (Ideally 2 years of experience)

• Proficiency in mathematical modeling using differential equations and programming as demonstrated by hands-on experience in a variety of computational tools such as MATLAB, Julia and R (MATLAB preferred).

• Strong commitment to on-the-job-training.

• Experience in drug discovery/development a plus, especially in quantitative aspects such as bioinformatics or pharmacometrics.

• Excellent oral and written communication skills.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) !

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo)

As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live.

All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)