Job Information
GlaxoSmithKline LLC Director, Flow Cytometry US Group Leader in Collegeville, Pennsylvania
Reference #: 392801 Site Name: USA - Pennsylvania - Upper Providence Posted Date: Apr 1 2024
This role will be located in Collegeville, PA and will require the new employee to work 5 days a week onsite to support our employees working in the Laboratory.
We are looking for a highly motivated, agile and experienced immunologist to lead our Cellular Biomarkers Flow Cytometry team within the Biomarker and Bioanalytical Platforms department. Our group is responsible for developing and validating complex multi-parameter biomarker assays for use in clinical studies. We generate deep immunophenotyping data to evaluate disease heterogeneity, drug-target engagement, drug mechanism of action and patient responses.
The successful Director, Flow Cytometry US Group Leader will have a deep understanding of immunology and will serve both as a group leader and as a technical expert.
Key Responsibilities This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following:
Provide scientific leadership and guide the development and validation of various high parameter spectral (Cytek Aurora) flow cytometry assays including deep immunophenotyping of immune cell subsets and receptor occupancy endpoints.
Oversee all aspects of method development, troubleshooting, validation and sample analysis for those clinical studies withflow cytometry endpoints.
Manage, develop and train a team of PhD and non-PhD scientists
Provide biomarker/translational expertise on multiple clinical programs/projects including influencing biomarker strategy
Be responsible for delivery of robust, high-quality data packages
Ensure all work is conducted in compliance with GCLP regulations and follow the appropriate SOPs.
Guide your team in successful interactions with CRO partners to assist in the delivery of high-quality clinical flow cytometry endpoints
Deliver, interpret and communicate complex scientific data to project/program teams within agreed timelines
Ability to handle multiple projects concurrently
Able to function well in a team and possess a good balance of creative and analytical skills
Contribute to capital equipment discussion
Lead efforts to investigate novel flow cytometry data analysis platforms and embed them within the organization
Why You? Minimum Qualifications: We are looking for professionals with these required skills to achieve our goals:
PhD in immunology, cell biology or similar field
6 or more years post-PhD work experience in immunology, cell biology, or biomedical science
Experience in biomarker/translational work on multiple clinical programs/projects
People leadership experience and ability to manage and effectively lead a team of PhD and non-PhD level scientists
Experience in immunology covering phenotyping of multiple lineages of cells
Laboratory experience working with clinical and non-clinical flow cytometry biomarker assay development, validation, and implementation
Experience in flow cytometry and in the design and execution 16+ color flow cytometry panels
Experience in the use of flow cytometry analysis software like OMIQ
Experience working with a variety of sample types including whole blood, PBMC, cell lines and single-cell suspension from tissue samples
Preferred Qualifications: If you have the following characteristics, it would be a plus:
Excellent collaboration and interpersonal skills to influence biomarker testing strategies and communicate efficiently with colleagues from all phases of clinical drug development
Ability to maintain a disciplined approach, ensuring a relentless focus on quality, compliance, scientific rigor, and operational excellence
Ability to problem solve and troubleshoot
Demonstrated judgment and decision making, especially for prioritizing multiple requests
Experience in the development and validation of novel flow cytometry assays to support clinical measurements and their translation to a companion diagnostic (CDx) when applicable.
Experience of working with external vendors for the transfer of assays to support clinical trial sample analysis and development of CDx (where appropriate)
Experience to design and execute 25+ color flow cytometry panels
Hands on experience with the Cytek Aurora
Hands on experience with OMIQ
Proactively demonstrate the ability to work to tight deadlines
Please visit to learn more about the comprehensive benefits program GSK offers US employees.
Why Us? GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
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