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The Children's Hospital of Philadelphia Research Technician I-Leukodystrophy Center in Philadelphia, Pennsylvania

Reference #: 1008875 SHIFT:Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP's Commitment to Diversity, Equity, and Inclusion

CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

A Brief Overview The Research Technician I will support the translational science component of the Leukodystrophy Center, a cutting-edge translational program at the Children's Hospital of Philadelphia. Researchers in the Leukodystrophy Center are currently focused on uncovering novel genetic etiologies within this group of disorders, identifying key biomarkers, and developing a repository of natural history data to support clinical trial development. Current projects leverage both in vivo and in vitro models for key conditions such as Hypomyelination and Atrophy of Basal Ganglia and Cerebellum (H-ABC), Aicardi-Goutieres Syndrome (AGS), and Alexander Disease.

The Research Technician I will work under the supervision of more experienced research technicians, assistants, post-doctoral fellows, and senior scientific staff to support key functions of a multi-center biorepository. Routine responsibilities may include specimen transport/shipping, sample processing (inc. DNA/RNA extraction, PBMC purification, etc.), cell culture work, and data entry into a REDCap-based biorepository database. Once proficiency has been attained for these basic tasks, the Research Technician I will have an opportunity to be trained in more advanced in vivo and in vitro techniques used in the Leukodystrophy center.

The Leukodystrophy Center's research program is high-volume and fast-paced, and a successful candidate must be able to demonstrate an ability to multi-task. Prior experience in a large basic science laboratory is strongly preferred. Outstanding written and oral communication skills are essential, as the position involves regular contact with collaborators within and externally to the Children's Hospital of Philadelphia. The Leukodystrophy Center is a founding member of the Global Leukodystrophy Initiative Clinical Trials Network (GLIA-CTN), a Rare Diseases Clinical Research Network (RDCRN) consortium funded under grant number U54NS115052 as a collaboration between the National Center for Advancing Translational Sciences (NCATS) and the National Institute of Neurological Disorders and Stroke (NINDS).

What you will do Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee. Performs research procedures on experimental samples as directed Records and checks experiments/results for completeness and accuracy Performs calculations and maintains appropriate log and lab notebooks Performs tasks that may require minimal familiarity with fundamental techniques and lab equipment Assists in care of lab equipment Sterilizes and cleans glassware, and disposes of specimens, media and other materials using appropriate procedures Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques Records results, organizes data and maintains lab notebook (physical or lectronic) in an organized manner. Conducts literary searches as directed. Education Qualifications High School Diploma / GED Required Associate's Degree Preferred Bachelor's Degree Preferred Experience Qualifications Related classroom or laboratory experience or successful completion of a technical training program (eg. Wistar, WPSI) Required At least six (6) months Related classroom or laboratory experience or successful completion of a technical training program (eg. Wistar, WPSI) Preferred Skills and Abilities Basic understanding of lab procedures, protocols, and equipment. Strong verbal and written communications skills Strong organizational skills Solid critical thinking / problem-solving skills Solid analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine.

Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.

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Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

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